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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > UGT1A6 antibody - C-terminal region
UGT1A6 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P19224 |
| Other Accession | NM_001072, NP_001063 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Sheep, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Zebrafish, Sheep, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 58kDa |
| Gene ID | 54578 |
|---|---|
| Alias Symbol | GNT1, HLUGP, HLUGP1, MGC29860, UDPGT, UGT1, UGT1F, UGT1A6S, UDPGT 1-6 |
| Other Names | UDP-glucuronosyltransferase 1-6, UDPGT 1-6, UGT1*6, UGT1-06, UGT1.6, 2.4.1.17, Phenol-metabolizing UDP-glucuronosyltransferase, UDP-glucuronosyltransferase 1-F, UGT-1F, UGT1F, UDP-glucuronosyltransferase 1A6, UGT1A6, GNT1, UGT1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-UGT1A6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | UGT1A6 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UGT1A6 (HGNC:12538) |
|---|---|
| Synonyms | GNT1, UGT1 |
| Function | [Isoform 1]: UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to facilitate their inactivation and excretion from the body (PubMed:15231852, PubMed:21422672). Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds (PubMed:15231852, PubMed:21422672). Involved in the glucuronidation of arachidonic acid (AA) and AA-derived eicosanoids including 15-HETE and 20-HETE (PubMed:15231852). Conjugates small planar phenolic molecules such as 4-nitrophenol, 1-naphthol, and 4- methylumbelliferone. The bulky phenol 4-hydroxybiphenyl, androgens and estrogens are not substrates. 2-hydroxybiphenyl is an excellent substrate (By similarity). Involved in the glucuronidation of the phytochemical ferulic acid at the phenolic or the carboxylic acid group (PubMed:21422672). |
| Cellular Location | Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein |
| Tissue Location | Expressed in skin. Isoforms 1 and 3 are expressed in kidney and liver. Isoform 1 but not isoform 2 is expressed in colon, esophagus and small intestine. |
Research Areas
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Application Protocols
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$ 389.00
Cat# AI11899
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